Publications

Glucose Deprivation Induces ATF4-Mediated Apoptosis through TRAIL Death Receptors.
Raffaella Iurlaro, Franziska Püschel, Clara Lucía León-Annicchiarico, Hazel O’Connor, Seamus J. Martin, Daniel Palou-Gramón, Estefanía Lucendo and Cristina Muñoz-Pinedo
Molecular and cellular Biology

Control of the Unfolded Protein Response in Health and Disease
Doultsinos D, Avril T, Lhomond S, Dejeans N, Guédat P, Chevet E.
SLAS Discov. 2017 Apr

Mitochondria-Associated Membranes As Networking Platforms and Regulators of Cancer Cell Fate
Maria Livia Sassano, Alexander R. van Vliet and Patrizia Agostinis
Frontiers in Oncology 2017

In the hunger games, the winner takes everything
Franziska Püschel and Cristina Muñoz Pinedo
TIBS (in press)

Driving cancer tumorigenesis and metastasis through UPR signaling
Alexandra Papaioannou and Eric Chevet
Current Topics in Microbiology and Immunology

Trial Watch: Immunogenic cell death induction by anticancer chemotherapeutics
Abhishek D. Garg, Sanket More, Nicole Rufo, Odeta Mece, Maria Livia Sassano, Patrizia Agostinis, Laurence Zitvogel, Guido Kroemer & Lorenzo Galluzzi
OncoImmunology

Dual IRE1 RNase functions dictate glioblastoma development
Stéphanie Lhomond, Tony Avril, Nicolas Dejeans, Konstantinos Voutetakis, Dimitrios Doultsinos, Mari McMahon, Raphaël Pineau, Joanna Obacz, Olga Papadodima, Florence Jouan, Heloise Bourien, Marianthi Logotheti, Gwénaële Jégou, Néstor Pallares‐Lupon, Kathleen Schmit, Pierre‐Jean Le Reste, Amandine Etcheverry, Jean Mosser, Kim Barroso, Elodie Vauléon, Marion Maurel, Afshin Samali, John B Patterson, Olivier Pluquet, Claudio Hetz, Véronique Quillien, Aristotelis Chatziioannou, Eric Chevet
EMBO Molecular Medicine

Bax retrotranslocation potentiates Bcl-xL’s antiapoptotic activity and is essential for switch-like transitions between MOMP competency and resistance
Annika Hantusch, Kushal K. Das, Ana J. García-Sáez, Thomas Brunner and Markus Rehm
Cell Death and Disease

Amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease (AD) are characterised by differential activation of ER stress pathways: focus on UPR target genes
L. Montibeller1 & J. de Belleroche
Cell Stress and Chaperones

Alterations of EDEM1 functions enhance ATF6 pro-survival signaling
Papaioannou A, Higa A, Jégou G, Jouan F, Pineau R, Saas L, Avril T, Pluquet O, Chevet E.
The FEBS Journal

Endoplasmic Reticulum Stress signalling – from basic mechanisms to clinical applications
Aitor Almanza Antonio Carlesso Chetan Chintha Stuart Creedican Dimitrios Doultsinos Brian Leuzzi Andreia Luís Nicole McCarthy Luigi Montibeller Sanket More Alexandra Papaioannou Franziska Püschel Maria Livia Sassano Josip Skoko Patrizia Agostinis Jackie de Belleroche Leif A. Eriksson Simone Fulda Adrienne M Gorman Sandra Healy Andrey Kozlov Cristina Muñoz‐Pinedo Markus Rehm Eric Chevet Afshin Samali
The FEBS Journal

Binding Analysis of the Inositol-Requiring Enzyme 1 Kinase Domain
Antonio Carlesso, Chetan Chintha, Adrienne M. Gorman, Afshin Samali, and Leif A. Eriksson
ACS Omega

Post-treatment de-phosphorylation of p53 correlates with dasatinib responsiveness in malignant melanoma
Josip Skoko, Jan Rožanc, Emilie M. Charles, Leonidas G. Alexopoulos, and Markus Rehm
BMC Cell Biology

Smac mimetic suppresses tunicamycin-induced apoptosis via resolution of ER stress
Behnaz Ahangarian Abhari*, Nicole McCarthy*, Marie Le Berre, Michelle Kilcoyne, Lokesh Joshi,Patrizia Agostinis and Simone Fulda
Cell Death and Disease

NF-κB contributes to Smac mimetic-conferred protection from tunicamycin-induced apoptosis
Abhari BA, McCarthy N, Agostinis P, Fulda S
Apoptosis